Phenoxyethanol is a preservative that's primarily used in skin and cosmetic products. It's also used in some medications involving ear diseases. Phenoxyethanol Description Phenoxyethanol is a widely used synthetic preservative with global approval for use in rinse-off or leave-on cosmetic products in concentrations up to 1%. Phenoxyethanol in skin care is used as a preservative. Phenoxyethanol is commonly used as a preservative in skincare because it is a substance that has broad-spectrum antimicrobial activity against bacteria, yeasts, and mold. It can be considered as one of the most well-tolerated preservatives used in cosmetic products" . 1 It is effective against various Gram-negative and Gram-positive bacteria, as well as against yeasts, and has only a weak inhibitory effect on resident skin flora. Phenoxyethanol is a commonly known contact allergen. Phenoxyethanol breaks down to phenol and acetaldehyde, acetaldehyde converts to acetate. Moreover, it is an easily accessible alternative . 3. 105) reported that 2-phenoxyethanol is a fragrance ingredient used in many fragrance mixtures (see discussion). It is known to prevent the growth of different microbes like bacteria, yeast, and molds. It is often used together with quaternary ammonium compounds . Phenoxyethanol is a synthetically produced ingredient, mainly used as a preservative. Use restrictions (moderate), Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high) fragrance ingredient and preservative. These properties help to prevent the growth of yeast, bacterial organisms and molds. Best added below 40°C (104°F) Oil; low water solubility. Phenoxyethanol, or 2-phenoxyethanol, has a large spectrum of antimicrobial activity and has been widely used as a preservative in cosmetic products for decades. Worst: Jergens Lotion Enriched Cream Hand Soap . Phenoxyethanol, also known as ethylene glycol monophenyl ether, is a clear, oily liquid with a faint floral odor. Natural sources of phenoxyethanol. Phenoxyethanol (and) Benzoic Acid (and) Dehydroacetic Acid. In skincare, this ingredient is mostly used as a preservative. Reports of contact allergy increased in the 1990s and 2000s which could be simply due to its increased use in products. As stated above, it can be found in a wide range of products including skin care products, makeup and personal care items, as well as vaccines and other medical supplies. Phenoxyethanol can be used as a fixative . This compound can be found naturally (like in green tea) but it is usually synthesized for commercial use. [1] Exposure to phenoxyethanol has been linked to reactions ranging from eczema [2] to severe, life-threatening allergic reactions. Phenoxyethanol is inactivated by highly ethoxylated compounds including polysorbates so do not use with surfactants. Every brand we carry at Follain has either never used phenoxyethanol, or as of today . Answer (1 of 3): Phenoxyethanol is a colorless liquid with a pleasant odor. Phenoxyethanol is stable up to 85°C (185°F) and has . Phenoxyethanol is a widely used synthetic preservative with global approval for use in rinse-off or leave-on cosmetic products in concentrations up to 1%. Caprylyl Glycol. Phenoxyethanol helps to prevent fungi, bacteria, and yeast from growing in your products. Sadly, Phenoxyethanol is popularly known for being harmful as some use cases have proven to cause severe eye irritation and redness, numbness, and dryness of the skin. Undiluted phenoxyethanol, which is never used in cosmetics, has been shown to induce mild-to-moderate irritation in animals studies conducted in rabbits and guinea pigs. Use restrictions (moderate), Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high) fragrance ingredient and preservative. It is also used as a fragrance stabiliser. 2-phenoxyethanol is an aromatic ether that is phenol substituted on oxygen by a 2-hydroxyethyl group. Phenoxyethanol is a really inexpensive ingredient that's good at broad-spectrum product preservation, says Jeannie, which is why brands use it. Has Antimicrobial Properties. Phenoxyethanol has germicidal and germistatic properties. Optiphen PLUS is a patent-pending liquid preservative from ISP/Sutton which offers broad spectrum preservation without parabens or formaldehyde. Phenoxyethanol is a colorless liquid with a pleasant odor. Some vaccines contain small amounts of formaldehyde, aluminum, gelatin, urea, potassium phosphate, human albumin, polysorbate 80, 2-phenoxyethanol, yeast protein and monosodium L-glutamate but the . Phenoxyethanol is a synthetically produced ingredient, mainly used as a preservative. If your cosmetics products aren't preserved. Prevents bacteria: It's antimicrobial and highly effective in preventing the growth of fungi, bacteria, and yeast in a product formula. Even highly diluted solutions (1% to 2%) may cause severe burns in case of prolonged contact. That is why ethylhexylglycerin is promoted by reputable companies as a "preservative booster." Some less reliable companies market it as a preservative. It is also naturally present in green tea and chicory. Phenoxyethanol is an aromatic ether and is a common preservative found in cosmetics, toiletries, perfumes, and other beauty products. It has a variety of unique properties that help inhibit the growth of undesirable microorganisms in skincare, hair care, and beauty products. In the simplest terms, Phenoxyethanol is used to fight bacteria. Phenoxyethanol is most active against Gram-negative bacteria. Click to see full answer. Also known as 2-phenoxyethanol, it is a member of the glycol ether family and is the product of the reaction of carcinogenic ethylene oxide with highly corrosive phenol. Chlorphenesin is a preservative that is used in a variety of cosmetics and skincare products. Phenoxyethanol is a preservative used in cosmetics and personal care products. Phenoxyethanol is also sometimes used as a solvent for dyes, inks, cellulose acetate, and resins. The use of chlorofluorocarbon propellants in cosmetic aerosol products intended for domestic consumption is prohibited (21 CFR 700.23). It has an oily, slightly sticky liquid texture and a faint rose scent. They are there to prevent chemical reactions taking place within the vaccine. This is known as making a "nature identical" chemical. The product's Material Safety Data Sheet (MSDS) says that it phenoxyethanol is harmful if swallowed, inhaled or absorbed through the skin and that it can cause reproductive damage. Parabens Alternative #8: Phenoxyethanol. The addition of ethylhexylglycerin affects the interfacial tension at the cellmembrane of microorganisms, improving the preservativeactivity of phenoxyethanol. It derives from a phenol. Phenoxyethanol is a solvent with high boiling point and low volatility. : AC130240000; AC130240010; AC130240025; AC130240050; AC130240051; AC130240250; AC130242500 CAS No 122-99-6 Synonyms Ethylene glycol monophenyl ether Recommended Use Laboratory chemicals. Phenoxyethanol is incredibly versatile in that it works in a large range of formulas and pH ranges . Because of its antimicrobial properties, it's primarily used as a preservative in cosmetics and pharmaceuticals. Given that, it is at best ironic, that phenoxyethanol is used as an anti-bacterial in vaccines. Caprylyl glycol provides moisturizing, emollient and saturating properties to many cosmetic solutions. Synthetic phenoxyethanol is made by reacting phenol, a mildly acidic petroleum derived chemical, with ethylene oxide, a proven human carcinogen, in an alkaline medium. The researchers did a specific phenoxyethanol skin test and found that she was . Uses advised against Food, drug, pesticide or biocidal product use. Because it can dissolve in both water and oil, phenoxyethanol has been used more and more in the light industry and daily chemical fields in recent years. The United States once had a recall of a product due to this ingredient. Phenoxyethanol is primarily used as a preservative and stabilizer. Similar to parabens, phenoxyethanol prevents the growth of yeast, bacteria and mold, extends product shelf life, and prevents user contamination. (ref. It is not a preservative. It is generally used in combination with other preservatives, in part because its activity is weak against yeast and Mould. . 2-phenoxyethanol (EU), or PE, is the most commonly used globally-approved preservative in personal care formulations. Not suitable for anhydrous products. Nevertheless, it's not entirely safe for your hair. Optiphen+ is a unique paraben-free and formaldehyde-free liquid preservative system which consists of Phenoxyethanol in an emollient base of Caprylyl Glycol. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). Phenoxyethanol & Ethylhexylglycerin is a liquid cosmetic preservative based on phenoxyethanol and ethylhexylglycerin. pH range is 3 to 10 and it is inactivated by highly ethoxylated compounds. All forms of phenol may cause irritation. Phenoxyethanol (PE) is a preservative found naturally occurring in green tea and chicory. Its low toxicity and its excellent bactericidal and bacteriostatic properties make 2-Phenoxyethanol highly valued in pharmaceutical applications. The preservative has a broad, balanced spectrum of effect against . Phenoxyethanol, also known as 2-phenoxyethanol, is an ether and aromatic alcohol, belonging to the glycol ethers family, that has been used as a preservative in cosmetics and personal care products since the 1950s. Its primary use, as a preservative is to improve shelf life and prevent contamination through use in order to improve the safety of the product. 27, 28 Additionally . Antimicrobial testing is a time consuming and cost-intensive but essential method for evaluation of newly developed pharmaceutical formulations for topical use. It's often used in even lower amounts, especially when combined with other preservatives. According to another publication: "Phenoxyethanol is a rare sensitizer. Phenoxyethanol is an ether alcohol with aromatic properties. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and anesthetic in fish aquaculture. Optiphen is a liquid, paraben-free and formaldehyde-free preservative used in aqueous formulations, anhydrous formulations, and in emulsions. 1. Phenoxyethanol, or 2-phenoxyethanol, has a large spectrum of antimicrobial activity and has been widely used as a preservative in cosmetic products for decades. 2-phenoxyethanol is a colorless, clear, oily liquid with a faint aromatic odor at room temperature and a low water solubility and evaporation rate. For commercial purposes, phenoxyethanol has been synthetically re-created in a laboratory. It is a primary alcohol, a glycol ether and an aromatic ether. But FDA 's recommended dosage for safe use in cosmetic products that contain Phenoxyethanol is at a 1% or less concentration which in many cases cosmetologists use . The MSDS refers to 100% concentrations. Phenoxyethanol is generally recognized as a safe, well-tolerated preservative.Yet, there have been a few reports of this substance causing adverse effects. It is said to be oily in texture, colorless, and has a rose-like odor. Phenoxyethanol. Phenoxyethanol is primarily used as a preservative and stabilizer. Phenoxyethanol is one of the most commonly used synthetic preservatives in skin care and cosmetic products, and is also used as a fixative for perfumes, insect repellent, and as a solvent. Phenoxyethanol is commonly used as a preservative in cosmetic products to limit the growth of bacteria. It has an oily, slightly sticky liquid texture and a faint rose scent. What's The Problem With Using Phenoxyethanol In Skincare? Phenoxyethanol is easily absorbed by the skin and is known to be neurotoxic if inhaled or digested (so it's banned from babycare products). It is both naturally foun. Broad spectrum preservation at pH 6 or lower. It has been used as a cosmetic preservative in makeup, skin care, perfumes, soaps, and detergents since the 1950s, and is also commonly found in vaccines and textiles. Scognamiglio et al. 0.4-1.2%. It's often used as a preservative or stabilizer for other ingredients that might otherwise deteriorate, spoil, or become less. Phenoxyethanol is used as a preservative in cosmetic products and also as a stabilizer in perfumes and soaps. This is where phenoxyethanol helps. What's worse - the product might smell and look just fine but be swarming with bacteria or fungi that are dangerous to your health. The chemical compound phenoxyethanol can be found naturally in green tea and chicory, but the version used in skin care products is a synthetically produced version in a lab. Phenoxyethanol is a preservative which is most active against gram-negative and gram-positive bacteria. Phenoxyethanol is the new preservative on the block - and already super popular. This is another chemical that is commonly used as a preservative in shampoo and other cosmetics. Phenoxyethanol is used as a preservative in cosmetic products to limit bacterial growth. Due to its multi-purpose . Phenoxyethanol. It is used as a preservative in a wide variety of both leave-on and rinse-off cosmetics and personal care products, including skin care, eye makeup, fragrances, blushers, foundations, lipstick, bath soaps, and detergents, among others. Here is a good study which looks at the mechanism of action of ethylhexylglycerin and how it boosts the effects of phenoxyethanol. The preservativeactivity of Phenoxyethanol in shampoo and other cosmetics reviewed by experts worldwide who have it! 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